Abstracts & Posters

Thank you to all applicants who submitted abstracts to be part of this year's NICER Symposium. Two recipients will be chosen for the Best Overall Abstract Award and Best Case Report Award.

Best Overall Abstract

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 “RELEVANCE OF MONITORING THYMIC FUNCTION AND RECOVERY IN INTERPRETING IMMUNE RECONSTITUTION POST HEMATOPOIETIC CELL TRANSPLANTATION IN INBORN ERRORS OF IMMUNITY”, based on its instructive capacity to highlight the collaboration between institutions when answering research questions and leading to improved patient care.

Daniel Drozdov, MD, MS

Fellow

Pediatric Blood and Marrow Transplant and Cellular Therapy

University of Minnesota

Best Case Report 

ADMINISTRATION OF MAVORIXAFOR, AN ORALLY AVAILABLE CXCR4 ANTAGONIST, INCREASES TOTAL WHITE BLOOD CELL, NEUTROPHIL, LYMPHOCYTE, AND MONOCYTE COUNTS ACROSS DIFFERENT DISEASE STATES

Authors: D.C. Dale*, Department of Medicine, University of Washington, Seattle, WA; D.F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; D. Cadavid, X4 Pharmaceuticals, Boston, MA; K. Walkovich, University of Michigan, Ann Arbor, MI; J.T. Warren, Division of Hematology-Oncology, Department of Pediatrics, Washington University, St. Louis, MO; J. Matous, Colorado Blood Cancer Institute, Sarah Cannon Research Institute, Denver, CO; X. Luo, X4 Pharmaceuticals, Boston, MA; V. Garg, X4 Pharmaceuticals, Boston, MA; W. Tang, X4 Pharmaceuticals, Boston, MA; H. Jiang, X4 Pharmaceuticals, Boston, MA; K. Chen, X4 Pharmaceuticals, Boston, MA; A.G. Taveras, X4 Pharmaceuticals, Boston, MA; M. Tillinger, X4 Pharmaceuticals, Boston, MA; Y. Hu, X4 Pharmaceuticals, Boston, MA; J. Donadieu, Department of Pediatric Hematology-Oncology, Reference Center for Chronic Neutropenia, National Registry of Congenital Neutropenia, Paris, France, Sorbonne University, Armand Trousseau Hospital APHP, Paris, France

p53-independent pathways in Diamond Blackfan Anemia

Lei Yu1, Susan Hammoud1, Ghazi Saroya2, Greggory Myers1, Yu Wang1, Ginette Balbin-Cuesta1, Vesa Kaartinen2, Rami Khoriaty1,3, James Douglas Engel1, Sharon A. Singh4*

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

INTERPRETATION OF THYMIC FUNCTION: DEFINING AGE-RELATED NORMATIVE VALUES FOR CD4+ RECENT THYMIC EMIGRANTS AND T CELL RECEPTOR EXCISION CIRCLES IN HEALTHY CHILDREN AND ADULTS

Amrita Basu PhD1,*,@ Dustin R. Bunch PhD1,@, #, Michelle Van Hee BS2, Xiangyang Dong PhD3, Daniel Drozdov MD4, Christen L. Ebens MD4,^ Roshini S. Abraham PhD1,*,#, ^ 1Department of Pathology and Laboratory Medicine, *Nationwide Children's Hospital, Columbus, OH, #Department of Pathology, Ohio State University, Columbus, OH, 2Mayo Clinic, Rochester, MN, 3Quest Diagnostics, Lewisville, TX, 4Division of Pediatric Hematology, University of Minnesota, Minneapolis, MN @Co-first authors; ^Co-senior authors; *Presenting author

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA

MECHANISTIC INSIGHT INTO THE SECRETION OF NEUTROPHIL EXTRACELLULAR TRAPS IN CHEMOTAXING NEUTROPHILS

S.B. Arya1,2, S.P. Collie3, and C.A. Parent*,1,2,4,5 1Life Sciences Institute, 2Department of Pharmacology, 3Cellular and Molecular Biology Graduate Program, 4Department of Cell and Developmental Biology, and 5Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA